AXOFIT-G300 METHYLCOBALAMIN + GABAPENTIN+ ALPHA LIPOIC ACID
Mode of Actions:
- Gabapentin+Methylcobalamin+Alpha Lipoic Acid is used in the treatment of neuropathic pain.
- Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyano at the cobalt is replaced with a methyl group.
- Methylcobalamin features an octahedral cobalt centre and can be obtained as bright red crystals from the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal-alkyl bonds.
- Nickel-methyl intermediates have been proposed for the final step of methanogenesis.
- Gabapentin is a medication which is used to treat partial seizures, neuropathic pain, hot flashes, and restless legs syndrome.
- Lipoic acid (LA), also known as α-lipoic acid and alpha lipoic acid (ALA) and thioctic acid is an organosulfur compound derived from caprylic acid (octanoic acid).
- ALA is made in animals normally, and is essential for aerobic metabolism.
Indications:
- Methylcobalamin,this vitamin functions in the environment to reduce the toxicity of heavy metals in the air, water, and soil. In the human body, this compound has been found to possess neuro-protective and anti-aging properties.
- It supports nerve function and neuron health in the brain and contributes improved signalling in the central nervous system. This is especially true in patients who have degenerative neurological conditions such as those that affect the myelin sheath like multiple sclerosis (MS).
- Gabapentin is an anti-seizure (anti-convulsant) drug that is used for preventing seizures and for treating post-herpetic neuralgia, the pain that follows an episode of shingles.
- It is recommended as one of a number of first-line medications for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central neuropathic pain.
- About 15% of those given gabapentin for diabetic neuropathy or postherpetic neuralgia have a measurable benefit, Gabapentin is taken by mouth.
- Alpha-lipoic acid seems to help prevent certain kinds of cell damage in the body, and also restores vitamin levels such as vitamin E and vitamin C. There is also evidence that alpha-lipoic acid can improve the function and conduction of neurons in diabetes.
- Alpha-lipoic acid is used in the body to break down carbohydrates and to make energy for the other organs in the body.
- Alpha-lipoic acid seems to work as an antioxidant, which means that it might provide protection to the brain under conditions of damage or injury. The antioxidant effects might also be helpful in certain liver diseases.
This is a combination of three medicines: Gabapentin, Methylcobalamin and Alpha Lipoic Acid:
- Gabapentin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells.
- Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells.
- Alpha Lipoic Acid is a naturally occurring fatty acid which has a protective effect on brain and nerve tissue. Together, they relieve neuropathic pain (pain from damaged nerves).
Side effects:
Common side effects of methylcobalamin +gabapentin + alpha lipoic acid are Dizziness, Sleepiness, Tiredness, Uncoordinated body movements.
