MUPIZOLE MUPIROCIN 2% + METRONIDAZOLE 2%
Mode of Actions:
- Metronidazole + mupirocin is used in the treatment of bacterial skin infections.
- Mupirocin is a topically used antibiotic from a strain of Pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin disorders, nasal infections, and wound healing.
- Mupirocin is used as a topical treatment for bacterial skin infections, for example, furuncle, impetigo, open wounds, etc. It is also useful in the treatment of superficial methicillin-resistant Staphylococcus aureus (MRSA) infections.
- Metronidazole is an antibiotic that is used to treat a wide variety of infections. It works by stopping the growth of certain bacteria and parasites.
Indications:
Type of medicine: An antimicrobial skin preparation
Uses: Rosacea; infected skin ulcers and wound
This is a combination of two antibiotics: Metronidazole and Mupirocin.
- Mupirocin stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Together, they treat your infection effectively.
- Use this medication only on the skin. Clean and dry the affected area first. Then apply a small amount of ointment to the area 3 times a day, or as directed by your doctor. You may cover the treated area with a bandage.
- Mupirocin cream is indicated for the treatment of secondarily infected traumatic skin lesions (up to 10 cm in length or 100 cm2 in area) due to susceptible isolates of Staphylococcus aureus (S. aureus) and Streptococcus pyogenes (S. pyogenes).
- Metronidazole kills the bacteria and other microorganisms that cause infections by damaging the DNA.
- Metronidazole is indicated for the treatment of choice for symtopmatic intestinal and extraintestinal amebiasis as well as infections with Trichomonas vaginalis and Giardia lamblia. It is quickly and reliably effective against Gardnerella vaginosis.
- Metronidazole is combined with a second antibiotic for the treatment of mixed infections with aerobic germs and for pre-operative infection prophylaxis (colorectal and gynecological interventions).It can be an alternative to vancomycin in the treatment of mucous colitis. Imidazoles are also used against Helicobacter pylori in which case one has to expect resistant germs.
- Metronidazole is sometimes more efficient than sulfasalazine for Crohn's disease, however, the tolerance of long-term administration is not established.
Side effects:
Common side effects of metronidazole + mupirocin are Dry skin, Application site reactions (burning, irritation, itching and redness)
